Papers in refereed journals 

2020

Consciousness and the Dimensionality of DOC Patients via the Generalized Ising Model.

Abeyasinghe PM & Aiello M, Nichols ES, Cavaliere C, Fiorenza S, Orsola Masotta O Borrelli P, Owen AM, Estraneo A & Soddu A. JCM 2020.

Training skills in minimally invasive, robotic and open surgery: the brain activation as an opportunity of learning.

Pelizzo G & Cardinali L, Bonanno L, Marino S, Cavaliere C, Aiello M, Bramanti P, Soddu A & Calcaterra V. Eur. Surg. Res. 2020.

Neuroimaging of narcolepsy and primary hypersomnias.

Cavaliere C, Longarzo M, Fogel S, Engström M, Soddu A. The Neuroscientist, 2020 Feb 28: 1073858420905829.

A better characterization of near death experiences using text mining analyses.

Charland-Verville V & Ribeiro de Paula D, Martial C, Cassol H, Chronik B, Soddu A & Laureys S. PloS ONE 2020. 15(1): e0227402.

Organization of the commissural fiber system in congenital and late-onset blindness.

Cavaliere C, Aiello M, Soddu A, Laureys S, Reislev NL, Ptito M, Kupers R.  Neuroimage Clin. 2020, 25: 102133.

The emergence of integrated information, complexity, and ‘consciousness’ at criticality.

Popiel NJM & Khajehabdollahi S, Abeyasinghe PM, Riganello F, Nichols ES, Owen AM, Soddu A.  Entropy 2020, 22(3), 339.

Reconfiguration of large-scale functional connectivity in patients with disorders of consciousness.

Martinez, Rudas J, Demertzi A, Charland-Verville V, Soddu A, Laureys S, Gómez F. Brain Behav. 2020 Jan; 10(1):e1476.

2019

Time-Delay Latency of Resting-State Blood Oxygen Level-Dependent Signal Related to the Level of Consciousness in Patients with Severe Consciousness Impairment. 

Rudas J, Martinez D, Castellanos G, Demertzi A, Martial C, Carriere M, Aubinet C, Soddu A, Laureys S, Gomez F. Brain Connect. 2020 Mar;10(2):83-94. doi: 10.1089/brain.2019.0716.

What impact can hospitalization environment produce on the ANS functioning in patients with Unresponsive Wakefulness Syndrome? – 24-hour monitoring.

Riganello F, Napoletano G, Cortese MD, Arcuri F, Solano A, Lucca LF, Tonin P, Soddu A. Bran Ini. 2019; 33(10):1347-1353.

Circadian Rhythms and Measures of CNS/Autonomic Interaction

Riganello F, Prada V, Soddu A, Di Perri C, Sannita WG. Int J Environ Res Public Health. Jul 2;16(13).

Tinnitus distress: a paradoxical attention to the sound?

Kandeepan S, Maudoux A, Ribeiro de Paula D, Zheng JY, Cabay JE, Gómez F, Chronik BA, Ridder D, Vanneste S, Soddu A. Journal of Neurology 1-11. May 31.

2018

Modelling the structure-function relationship of the brain: A comparison between the 2-dimensional classical Ising model and the generalized Ising model. 

Abeyasinghe PM, Ribeiro de Paula D, Khajehabdollahi S, Valluri SR, Owen AM, Soddu A. Brain Connectivity 8:7, 444-455.

Multimodal neuroimaging approach to variability of functional connectivity in disorders of consciousness: a PET/MRI study.

Cavaliere C & Kandeepan S, Aiello M, Ribeiro de Paula D, Marchitelli R, Fiorenza S, Orsini M, Trojano L, Masotta O, St. Lawrence K, Loreto V, Chronik B, Nicolai E, Soddu A & Estraneo A. Frontiers in Neurology 9:861. Oct 18.

2017

Multifaceted brain networks reconfiguration in disorders of consciousness uncovered by co-activation patterns.

Di Perri C, Amico E, Heine L, Annen J, Martial C, Larroque SK, Soddu A, Marinazzo D, Laureys S. Hum Brain Mapp. Oct 11.

Spontaneous low frequency BOLD signal variations from resting-state fMRI are decreased in Alzheimer disease.

Kazemifar S, Manning K, Rajakumar N, Gómez F, Soddu A, Borrie MJ, Menon RS & Bartha R. PLoS One. 12(6): e0178529.

A method for Independent Component graph analysis of resting state fMRI.

Ribeiro de Paula D, Ziegler E, Abeyasinghe PM, Das TK, Cavaliere C, Aiello M, Heine L, di Perri C, Demertzi A, Noirhomme Q, Charland-Verville V, Vanhaudenhuyse A, Stender J, Gomez F, Tshibanda JFL, Laureys S, Owen AM, Soddu A. Brain Behav. 00:e00626.

“A good sleep for a fresh mind” in patients with acute traumatic brain injury.

Soddu A, Bassetti C. Invited Editorial. Neurology. 88(3), 226-227.

Sedation of patients with disorders of consciousness during neuroimaging: effects on resting state functional brain connectivity.

Kirsch M & Guldenmund P, Mohamed AB, Demertzi A, Baquero K, Heine L, Charland-Verville V, Vanhaudenhuyse A, Bruno MA, Gosseries O, Di Perri C, Ziegler E, Brichant JF, Soddu A, Bonomme V & Laureys S.  Anesthesia & Analgesia, 124(2):588–598.

A Principal Component Analysis of the Diffuse Interstellar Bands.

Ensor T, Cami J, Bhatt NH, Soddu A. The Astrophysical Journal, 836 (2), 162.

2016

Pain perception in unresponsive wakefulness syndrome may challenge the interruption of artificial nutrition and hydration: neuroethics in action.

Riganello F, Macri S, Alleva E, Petrini C, Soddu A, Leòn-Carriòn J, Dolce G. Front. Neurol. 7:202.

Functional connectivity substrates for tDCS response in Minimally Conscious State patients.

Cavaliere C, Aiello M, Di Perri C, Amico E, Martial C, Thibaut A & Laureys S & Soddu A. Front. Cell. Neurosci. 10:257.

Resting state network-specific breakdown of functional connectivity during ketamine alteration of consciousness.

Bonhomme V, Vanhaudenhuyse A, Demertzi A, Bruno MA, Jaquet O, Bahri MA, Plenevaux A, Boly M, Boveroux P, Soddu A, Brichant JF, Maquet P, Laureys S.  Anesthesiology. Nov;125(5):873-888.

Neural correlates of consciousness in patients who have emerged from a minimally conscious state: a cross-sectional multimodal imaging study.

Di Perri C, Bahri MA, Amico E, Thibaut A, Heine L, Antonopoulos G, Charland-Verville V, Wannez S, Gomez F, Hustinx R, Tshibanda L, Demertzi A & Soddu A & Laureys S. Lancet Neurol. S1474-4422(16)00111-3.

Propofol-Induced Frontal Cortex Disconnection: A Study of Resting-State Networks, Total Brain Connectivity, and Mean BOLD Signal Oscillation Frequencies.

Guldenmund P & Gantner IS, Baquero K, Das TK, Demertzi A, Boveroux P, Bonhomme V, Vanhaudenhuyse A, Bruno MA, Gosseries O, Noirhomme Q, Kirsch M, Boly M, Owen AM, Laureys S, Gómez F & Soddu A. Brain Connect. 6(3):225-37.

Brain damage in patients with disorders of consciousness: a voxel-based morphometry study.

Guldenmund P, Soddu A, Baquero K, Vanhaudenhuyse A, Bruno MA, Gosseries O, Laureys S, Gómez F. Brain Inj. 30(3):343-52.

2015

Correlation between resting state fMRI total neuronal activity and PET metabolism in healthy controls and patients with disorders of consciousness.

Soddu A & Gómez F, Heine L, Di Perri C, Bahri MA, Voss HU, Bruno MA, Vanhaudenhuyse A, Phillips C, Demertzi A, Chatelle C, Schrouff J, Thibaut A, Charland-Verville V, Noirhomme Q, Salmon E, Tshibanda JF, Schiff ND, Laureys S. Brain Behav. 6(1):e00424.

Prevalence of increases in functional connectivity in visual, somatosensory and language areas in congenital blindness.

Heine L, Bahri MA, Cavaliere C, Soddu A, Laureys S, Ptito M and Kupers R.  Front Neuroanat, 9: 86.

Intrinsic functional connectivity differentiates minimally conscious from unresponsive patients.

Demertzi A, Antonopoulos G, Heine L, Voss H, Crone JS, Kronbichler M, Trinka E, Los Angeles C, Bahri AM, Philips C, Di Perri C, Gomez F, Tshibanda L, Vanhaudenhuyse A, Charland-Verville V, Soddu A, Schiff N, Whitfield-Gabrieli S and Laureys S. Brain, 138 (Pt 9): 2619-31.

Diffusion tensor imaging and white matter abnormalities in patients with disorders of consciousness.

Cavaliere C, Aiello M, Di Perri C, Fernandez-Espejo D, Owen AM, Soddu A. Frontiers in Human Neuroscience; 8, 1028.

Cerebral functional connectivity periodically (de) synchronizes with anatomical constraints.

Liegeois R, Ziegler E, Geurts P, Gomez F, Bahri MA, Phillips C, Soddu A, Vanhaudenhuyse A, Laureys S, Sepulchre R. Brain Struct Funct. Jul 22.

Principal-component analysis of particle motion.

Chen HY, Liégeois R, de Bruyn J, and Soddu A. Phys. Rev. E. 91, 042308.

2014

Technology-based assessment in patients with disorders of consciousness.

Di Perri C, Heine L, Amico E, Soddu A, Laureys S, Demertzi A. Ann Ist Super Sanita. 50(3):209-20.

Highlighting the structure-function relationship of the brain with the Ising model and graph theory.

Das TK, Abeyasinghe PM, Crone JS, Sosnowski A, Laureys S, Owen AM, Soddu A. Biomed Res Int. 237898.

Measuring consciousness in coma and related states.

Di Perri C, Thibaut A, Heine L, Soddu A, Demertzi A, Laureys S. World J Radiol. 6(8):589-97.

Biased binomial assessment of cross-validated estimation of classification accuracies illustrated in diagnosis predictions.

Noirhomme Q, Lesenfants D, Gomez F, Soddu A, Jessica S, Garraux G, Luxen A, Phillips C, Laureys S. Neuroimage Clin. Apr 13. 4:687-94.

Lies, damned lies, and diagnoses: Estimating the clinical utility of assessments of covert awareness in the Vegetative State.

Cruse D, Gantner I, Soddu A, Owen AM. Brain Injury 28(9):1197-201.

Diagnostic precision of multimodal neuroimaging methods in disorders of consciousness – a clinical validation study.

Stender J, Gosseries O, Bruno MA, Charland-Verville V, Vanhaudenhuyse A, Demerzti A, Chatelle C, Thonnard M, Thibaut A, Heine L, Soddu A, Boly M, Schnakers C, Gjedde A, Laureys S. Apr 15. Lancet S0140-6736(14)60042-8.

Independent SSVEP-based brain-computer interface in locked-in syndrome.

Lesenfants D, Habbal D, Lugo Z, Lebeau M, Amico E, Horki P, Pokorny C, Gomez F, Soddu A, Mueller-Putz G, Laureys S, Noirhomme Q. J Neural Eng. Jun 11. (3):035002.

Multiple fMRI system-level baseline connectivity is disrupted in patients with consciousness alterations.

Demertzi A, Gómez F, Crone JS, Vanhaudenhuyse A, Tshibanda L, Noirhomme Q, Thonnard M, Charland-Verville V, Kirsch M, Laureys S & Soddu A. Cortex. Mar; 52:35-46.

The ‘accidental’ degeneracy of the hydrogen atom is no accident!

Deshmukh PC, Ganesan A, Shanthi N, Jones B, Nicholson J, Soddu A. Canadian Journal of Physics.

2013

Altered Network Properties of the Fronto-Parietal Network and the Thalamus in Impaired Consciousness.

Crone JS, Soddu A, Höller Y, Vanhaudenhuyse A, Schurz M, Bergmann J, Schmid E, Trinka E, Laureys S, Kronbichler M. Neuroimage Clin 4:240-8. Dec 26.

Changes in Effective Connectivity by Propofol Sedation.

Gómez F, Phillips C, Soddu A, Boly M, Boveroux P, Vanhaudenhuyse A, Bruno MA, Gosseries O, Bonhomme V, Laureys S, Noirhomme Q. PLoS One 8(8):e71370.

Thalamus, brainstem and salience network connectivity changes during mild propofol sedation and unconsciousness.

Guldenmund P, Demertzi A, Boveroux P, Boly M, Vanhaudenhuyse A, Bruno MA, Noirhomme Q, Brichant JF, Bonhomme V, Laureys S, Soddu A. Brain Connect. Apr 3.

2012

Consciousness supporting networks.

Demertzi A, Soddu A, Laureys S. Curr Opin Neurobiol. Dec 27.

A default mode of brain function in altered states of consciousness.

Guldenmund P, Vanhaudenhuyse A, Boly M, Laureys S, Soddu A. Arch Ital Biol. 150(2-3):107-21.

A role for the default mode network in the bases of disorders of consciousness.

Fernández-Espejo D, Soddu A, Cruse D, Palacios EM, Junque C, Vanhaudenhuyse A, Rivas E, Newcombe V, Menon D, Pickard J, Laureys S, Owen AM. Ann Neurol. 72(3):335-43.

Alterations of multiple resting state network connectivity in physiological, pharmacological and pathological consciousness states.

Heine L, Soddu A, Gomez F, Vanhaudenhuyse A, Charland-Verville V, Thonnard M, Kirsch M, Tshibanda L, Laureys S, Demertzi A. Resting state networks and consciousness. Front Psychol. 3:295.

Probing command following in patients with disorders of consciousness using a brain-computer interface.

Lulé D, Noirhomme Q, Kleih SC, Chatelle C, Halder S, Demertzi A, Bruno MA, Gosseries O, Vanhaudenhuyse A, Schnakers C, Thonnard M, Soddu A, Kübler A, Laureys S.  Clin Neurophysiol. Aug 21.

Resting state EEG study of comatose patients: a connectivity and frequency analysis to find differences between Vegetative and Minimally Conscious States.

Lehembre R & Bruno MA, Vanhaudenhuyse A, Chatelle C, Cologan V, Leclercq Y, Soddu A, Macq B, Laureys S, Noirhomme Q. Funct Neurol 27(1):41-7.

Reduction in inter-hemispheric connectivity in disorders of consciousness.

Ovadia-Caro S, Nir Y, Soddu A, Ramot M, Hesselmann G, Vanhaudenhuyse A, Dinstein I, Tshibanda JF, Boly M, Harel M, Laureys S, Malach R. PLoS One 7(5):e37238.

Connectivity graph analysis of the auditory resting state network in tinnitus.

Maudoux A, Lefebvre P, Demertzi A, Cabay JE, Vanhaudenhuyse A, Laureys S, Soddu A. Brain Res. 1485:10-21. Nov 16.

Auditory resting-state fMRI activity in tinnitus: an IC analysis.

Maudoux A, Lefebvre Ph, Cabay JE, Demertzi A, Vanhaudenhuyse A, Laureys S, Soddu A. PLoS One 7(5):e36222.

Brain connectivity in disorders of consciousness.

Boly M, Massimini M, Garrido MI, Gosseries O, Noirhomme Q, Laureys S, Soddu A. Brain Connect 2(1):1-10.

Pain Perception in Disorders of Consciousness: Neuroscience, Clinical Care, and Ethics in Dialogue.

Demertzi A, Racine E, Bruno MA, Ledoux D, Gosseries O, Vanhaudenhuyse A, Thonnard M, Soddu A, Moonen G, Laureys S. Neuroethics 1-14.

Identifying the Default Mode Component in Spatial IC Analysis of Patients with Disorders of Consciousness.

Soddu A, Vanhaudenhuyse A, Bahri M, Bruno MA, Boly M, Demertzi A, Tshibanda JF, Phillips C, Stanziano M, Ovadia-Caro S, Nir Y, Maquet P, Papa M, Malach R, Laureys S, Noirhomme Q. Hum Brain Mapp 33(4):778-96.

2011

Disorders of consciousness: what’s in a name?

Gosseries O, Bruno MA, Chatelle C, Vanhaudenhuyse A, Schnakers C, Soddu A, Laureys S. NeuroRehabilitation 28 (1):3-14.

Resting state activity in patients with disorders of consciousness.

Soddu A, Vanhaudenhuyse A, Demertzi A, Bruno MA, Tshibanda L, Di H, Boly M, Papa M, Laureys S, Noirhomme Q. Funct Neurol 36(1):37-43.

Post-anoxic vegetative state: imaging and prognostic perspectives.

Stanziano M, Foglia C, Soddu A, Gargano F, Papa M.  Funct Neurol 36(1):45-50.

The brain’s found self: experimental manipulation of resting state’s cerebral networks by means of hypnosis.

Demertzi A, Soddu A, Faymonville ME, Bahri M, Noirhomme Q, Laureys S, Prog Brain Res 193:309-22.

Multi-modal neuro-imaging in half brain functioning patients with disorders of consciousness.

Bruno MA, Fernández-Espejo D, Tshibanda L, Lehembre R, Vanhaudenhuyse A, Gosseries O, Lommers E, Noirhomme Q, Boly M, Owen A, Laureys S, Soddu A. Prog Brain Res 193:323-33.

Doing more with less: neural plasticity lessons from disordered states of consciousness.

Demertzi A, Schnakers C, Soddu A, Bruno MA, Gosseries O, Vanhaudenhuyse A, Laureys S. Frontiers in Consciousness Research 2.

Attitudes towards end-of-life issues in disorders of consciousness: a European survey.

Demertzi A, Bruno MA, Vanhaudenhuyse A, Gosseries O, Soddu A, Schnakers C, Moonen G, Laureys S. Journal of Neurology 258:1058-1065.

Two distinct neuronal networks mediate the awareness of environment and of self.

Vanhaudenhuyse A & Demertzi A, Schabus M, Noirhomme Q, Soddu A, Bredart S, Boly M, Phillips C, Luxen A, Moonen G, Laureys S. Journal of Cognitive Neuroscience 23:570-578.

Default network connectivity reflects the level of consciousness in non-communicative brain damaged patients.

Vanhaudenhuyse A & Noirhomme Q, Tshibanda L, Bruno MA, Boveroux P, Schnakers C, Soddu A, Perlbarg V, Ledoux D, Brichant JF, Moonen G, Phillips C, Maquet P, Greicius MD, Laureys S, Boly M. Brain 133(Pt 1):161-71.

2010

Disorders of consciousness: Moving from passive to resting state and active paradigms.

Bruno MA & Soddu A, Demertzi A, Laureys S, Gosseries O, Schnakers C, Boly M, Noirhomme Q, Thonnard M, Chatelle C, Vanhaudenhuyse A. Cognitive Neuroscience 1, 3:193-203.

Brain connectivity in pathological and pharmacological coma.

Noirhomme Q & Soddu A, Lehembre R, Vanhaudenhuyse A, Boveroux P, Boly M, Laureys S. Frontiers in systems neuroscience 4:160.

Neuroimaging after coma.

Tshibanda L, Vanhaudenhuyse A, Boly M, Soddu A, Bruno MA, Moonen G, Laureys S, Noirhomme Q. Neuroradiology Review 52(1):15-24.

Functional Neuroimaging Approaches to the Changing Borders of Consciousness.

Noirhomme Q, Soddu A, Vanhaudenhuyse A, Lehembre R, Bruno, MA, Gosseries O, Demertzi A, Maudoux A, Schnakers C, Boveroux P, Boly M, Laureys S. Journal of Psychophysiology 24(2):68-75.

2009

Reaching across the abyss: recent advances in functional magnetic resonance imaging (fMRI) and their potential relevance to disorders of consciousness.

Soddu A, Boly M, Nir Y, Noirhomme Q, Vanhaudenhuyse A, Demertzi A, Arzi A, Ovadia S, Stanziano M, Papa M, Laureys S, Malach R. Prog Brain Res 177:261-74.

MRI in coma survivors.

Tshibanda L, Vanhaudenhuyse A, Bruno MA, Boly M, Soddu A, Laureys S, Moonen G. Rev Med Liege 64 Spec No:42-8. French.

Bispectral Index correlates with regional cerebral blood flow during sleep.

Noirhomme Q, Boly M, Bonhomme V, Boveroux P, Phillips C, Peigneux P, Soddu A, Luxen A, Moonen G, Maquet P, Laureys S. Arch Ital Biol. 147: 51-7.

2007

Large time-dependent CP violation in B/s0 system and finite D0 – anti-D0 mass difference in four generation standard model.

Hou WS, Nagashima M, Soddu. Phys. Rev. D 76:016004.

2006

Four generation CP violation in B -> phi K0, pi0 K0, eta-prime K0 and hadronic uncertainties.

Hou WS, Nagashima M, Raz G, Soddu. JHEP 0609:012.

eV seesaw with four generations.

Hou WS, Soddu. Phys. Lett. B 638:229-233.

2005

Baryon number violation involving higher generations.

Hou WS, Nagashima M, Soddu. Phys. Rev. D 72:095001.

Enhanced K(L) —> pi0 nu anti-nu from direct CP violation in B —> K pi with four generations.

Hou WS, Nagashima M, Soddu. Phys. Rev. D 72:115007.

Difference in B+ and B0 direct CP asymmetry as effect of a fourth generation.

Hou WS, Nagashima M, Soddu. Phys. Rev. Lett 95:141601.

Complete CKM quark mixing via dimensional deconstruction.

Hung PQ, Soddu A, Tran. Nucl. Phys. B 712:325-346.

B —> J/psi K* in a supersymmetric right-handed flavor mixing scenario.

Hou WS, Nagashima M, Soddu. Phys. Rev. D 71:016007.

2004

Phenomenology of a quark mass matrix from six-dimensions and its implication for the strong CP problem.

Hung PQ, Seco M, Soddu. Nucl. Phys. B 692:83.

Democratic mass matrices from five-dimensions.

Soddu A, Tran. Phys. Rev. D 69:015010.

2002

Rare K decays in a model of quark and lepton masses.

Hung PQ, Soddu. Phys. Rev. D 65:054035.

1998

A New evaluation of the t —> cH decay width in the standard model.

Mele B, Petrarca S, Soddu. Phys. Lett. B 435:401-406.

Chapters in books:

2018

Anesthesia and Resting State Network (RSN)

Mortazavi N, Staquet C, Vanhaudenhuyse A, Soddu A, Feymoville ME, Bonhomme V. Edited by Ramachandran Ramani. Functional MRI: Basic Principles and Emerging Clinical Applications 2018:10.

2016

Biomedical Engineering and Nanoneurosurgery: From the Laboratory to the Operating Room.

Ganau M, Foroni RI, Soddu A, Ambu R. Handbook of Clinical Nanomedicine: Nanoparticles, Imaging, Therapy and Clinical Applications. Av Israel Rubinstein & Raj Bawa & Gerald F. Audette

Hybrid Imaging in Vegetative State.

Cavaliere C, Aiello M, Soddu A. PET-CT and PET- MRI in Neurology 247-249. Springer International Publishing.

2015

Imaging Correlations in Non-communicating Patients.

Heine L, Di Perri C, Soddu A, Gomez F, Laureys S, Demertzi A. Clinical Neurophysiology in Disorders of Consciousness 149-157. Springer Vienna.

Instrumental Assessment of Residual Consciousness in DOCs.

Cavaliere C, Di Perri C, Laureys S, Soddu A.  Neurotechnology and Direct Brain Communication: New insights and responsibilities concerning speechless but communicative subjects. Routledge – Taylor and Francis.

Sleep, Coma, Vegetative and Minimally Conscious States.

Di Perri C, Cavaliere C, Bodard O, Thibaut A, Bali MA, Soddu A, Laureys S. Sleep Disorders Medicine: Basic Science, Technical Considerations, and Clinical Aspects, 4th edition, Springer.

2013

Neuroimaging e alterazioni croniche della coscienza: al di la’ dell’impatto emotivo

Stanziano M, Papa M, Laureys S, Soddu A. Testamento Biologica. Ed Accademia dei Lincei.

2012

Spectroscopy and diffusion tensor imaging in disorders of consciousness.

  • Tshibanda JFL, Demertzi A, Soddu A. Comas et états de conscience altérée. Ed Caroline Schnakers & Steven Laureys.

Functional imaging in disorders of consciousness.

  • Vanhaudenhuyse A, Boly M, Bruno MA, Laureys S, Soddu A. Comas et états de conscience altérée. Ed Caroline Schnakers & Steven Laureys.